Name :
HNRNPH1 antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
HNRNPH1 Rabbit Polyclonal antibody. Positive WB detected in mouse brain tissue, HeLa cells, mouse embryonic stem cells. Positive IHC detected in human cervical cancer tissue. Observed molecular weight by Western-blot: 49 kDa
Tested applications :
ELISA, WB, IHC
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
DKFZp686A15170 antibody; hnRNP H antibody; hnRNPH antibody; HNRNPH1 antibody; HNRPH antibody; HNRPH1 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of HNRNPH1 recombinant protein (Accession Number: XM_017009416). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:500-1:5000IHC: 1:20-1:200
Background :
The heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. HNRNPH1 is one component of hnRNP complex and mediates pre-mRNA alternative splicing regulation [PMID:11003644]. Together with CUGBP1, it inhibits IR pre-mRNA exon 11 inclusion in myoblast [PMID: 16946708].
References :
Neumann M, Valori CF, Ansorge O. Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations. Acta neuropathologica. 124(5):705-16. 2012.
Related websites: https://www.medchemexpress.com/antibodies.html
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