Name :
KDM2B Polyclonal Antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Polyclonal antibody to KDM2B
Tested applications :
WB
Species reactivity :
Human
Alternative names :
KDM2B antibody; CXXC2 antibody; FBXL10 antibody; Fbl10 antibody; JHDM1B antibody; PCCX2 antibody; lysine demethylase 2B antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
Antigen: A synthetic peptide corresponding to a sequence within amino acids 600-700 of human KDM2B (XP_011537177.1).
Clonality :
Polyclonal
Formulation :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage instructions :
Store at -20℃. Avoid freeze / thaw cycles.
Applications :
WB 1:500 – 1:2000
Background :
Histone demethylase that demethylates ‘Lys-4’ and ‘Lys-36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ‘Lys-4’ and dimethylated H3 ‘Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ‘Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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