Name :
KDM5C antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
KDM5C Rabbit Polyclonal antibody. Positive WB detected in HeLa cells. Positive IF detected in HeLa cells. Observed molecular weight by Western-blot: 171-180 kDa
Tested applications :
ELISA, WB, IF
Species reactivity :
Human,Mouse,Rat; other species not tested.
Alternative names :
DXS1272E antibody; Histone demethylase JARID1C antibody; JARID1C antibody; KDM5C antibody; lysine (K) demethylase 5C antibody; Lysine specific demethylase 5C antibody; MRXJ antibody; MRXSJ antibody; Protein SmcX antibody; Protein Xe169 antibody; SMCX antibody; XE169 antibody
Immunogen :
Isotype :
Rabbit IgG
Preparation :
This antibody was obtained by immunization of KDM5C recombinant protein (Accession Number: NM_001282622). Purification method: Antigen affinity purified.
Clonality :
Polyclonal
Formulation :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage instructions :
Store at -20℃. DO NOT ALIQUOT
Applications :
Recommended Dilution: WB: 1:200-1:2000IF: 1:50-1:500
Background :
KDM5C belongs to the ARID protein family that harbors conserved DNA-binding motifs and acts as a histone H3 lysine 4 demethylase, suggesting a potential role in epigenetic regulation during development, cell growth and differentiation [PMID:21575681]KDM5C protein is homologous to three other proteins of the human JARID1 family (JARID1A, JARID1B and JARID1C). This family shares several evolutionarily conserved domains, including the catalytic JmjC domain, JmjN domain, Arid/Bright domain, C5HC2 zinc-finger domain and two plant homeodomains (PHD), a motif that binds methyl-lysine residues [PMID:17320160,17320161].
References :
Related websites: https://www.medchemexpress.com/antibodies.html
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