Name :
Anti-CAPG / AFCP antibody
Documents :
DataSheet Material Safety Data Sheets (MSDS)
Description :
Rabbit polyclonal to CAPG / AFCP
Tested applications :
ELISA, WB, IP
Species reactivity :
Human CAPG / AFCP
Alternative names :
capping protein (actin filament) antibody; gelsolin-like antibody; CAPG antibody; AFCP antibody; MCP antibody; actin regulatory protein CAP-G antibody; gelsolin-like capping protein antibody; macrophage capping protein antibody; capping protein (actin filament) antibody; gelsolin-like antibody; Capg antibody; gCap39 antibody; mbh1 antibody; actin regulatory protein CAP-G antibody; actin-capping protein GCAP39 antibody; macrophage-capping protein antibody; myc basic motif homolog 1 antibody; AFCP antibody; HEL-S-66 antibody; mbh1 antibody; gCap39 antibody; MCP antibody
Immunogen :
Human CAPG / AFCP recombinant protein
Isotype :
Rabbit IgG
Preparation :
Produced in rabbits immunized with purified, recombinant Human CAPG / AFCP (rh CAPG / AFCP; AAH14549.1; Met1-Lys348). CAPG / AFCP specific IgG was purified by Human CAPG / AFCP affinity chromatography.
Clonality :
Polyclonal
Formulation :
0.2 μm filtered solution in PBS
Storage instructions :
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Applications :
WB: 2-10 μg/mlELISA:0.1-0.2 μg/mLThis antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human CAPG / AFCP. The detection limit for Human CAPG / AFCP is IP: 1-4 μg/mg of lysate
Background :
CAPG, also known as actin Regulatory Protein CAPG, is a a member of the gelsolin/villin family. Members of this family are actin-regulatory proteins. CAPG reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, CAPG contributes to the control of actin-based motility in non-muscle cells. CAPG may also play an important role in macrophage function.
References :
Watari A. et al., 2007, Oncogene. 25 (56): 7373-80. De Corte V. et al., 2005, J Cell Sci. 117 (22): 5283-92. Van Impe K. et al., 2003, J Biol Chem. 278 (20): 17945-52.
Related websites: https://www.medchemexpress.com/antibodies.html
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