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Name :
Anti-Beclin 1 (4F4) Mouse antibody

Documents :
DataSheet Material Safety Data Sheets (MSDS)

Description :
Beclin 1 (4F4) Mouse monoclonal antibody

Tested applications :

Species reactivity :
Human, Mouse, Rat, Monkey, Hamster

Alternative names :
APG6;ATG 6;ATG6;ATG6 autophagy related 6 homolog;Bcl-2-interacting protein beclin;Beclin 1 (coiled coil moesin like BCL2 interacting protein);Beclin 1 autophagy related;Beclin-1;Beclin1;BECN 1;BECN1;BECN1_HUMAN;Coiled coil myosin like BCL2 interacting pro antibody

Immunogen :

Isotype :

Preparation :
Antigen: Purified recombinant human Beclin 1 protein fragments expressed in E.coli.

Clonality :

Formulation :
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4 150 mM NaCl) with 0.02% sodium azide 50% glycerol

Storage instructions :
Store at 4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

Applications :
WB: 1/1000

Background :
Swiss-Prot Acc.Q14457.Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

References :
Nrf2 protects against acute lung injury and inflammation by modulating TLR4 and Akt signaling.Effect of metformin on human periodontal ligament stem cells cultured with polydopamine-templated hydroxyapatite

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: Gardos- Channel