Product Name: Phospho-EIF2AK2-T446 Monoclonal Antibody
Host Species: Rabbit
Purity: Affinity purificationMedchemexpress
Isotype: IgG
Background: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits
Immunogen: A phospho specific peptide corresponding to residues surrounding T446 of human EIF2AK2
CAS NO:952021-60-2 Product: PF 477736
Swiss Prot: P19525
Synonyms: EIF2AK1;PKR;PPP1R83;PRKR
Calculated MW: 62kDa
Observed MW: Refer to figuresMyosin inhibitors
Reactivity: Human
Test Dapplications: WB IHC IF IP
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Postivie Samples: HeLa treated with calyculin A and TNF-α
Celluar Location: Cytoplasm,Nucleus,Cytoplasm,perinuclear regionPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25375373?dopt=Abstract
